The life expectancy of music

In music we have twelve notes. Perfect mathematical ratios. Of those twelve notes there has been millions upon millions of pieces of music and songs written for hundreds of years. So mathematically there should a day where any combination of these 12 notes will run out. Will there be a day when music itself can't be composed Will the combinations of musical frequencies simply run out? We see composers everyday sued for copyright infringements but perhaps it's not their fault maybe we are getting to point where no musical tunes can't be unique anymore. So is this thing that we love so much but take so much for granted have a life expectancy? Or is it like one of those "Is the universe finite?